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Vazopresin

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Vazopresin
Općenito
Hemijski spojVazopresin
Druga imenaAntidiuretski hormon (ADH); arginin-vazopresin (AVP); argipresin
IUPAC ime:1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oksoetil)-10-(3-amino-3-oksopropil)-13-benzil-16-(4-hidroksibenzil)-6,9,12,15,18-pentaoxo-1,2-ditia-5,8,11,14,17-pentaazacikloikosan-4-il]karbonil}-L-prolil-L-arginilglicinamid
Molekularna formulaC46H65N15O12S2
CAS registarski broj11000-17-2
Kratki opisPredominantno jetreni i bubrežni hormon, sa poluživotom od 10-20 minuta
Osobine1
Gustoća1,6±0.1
1 Gdje god je moguće korištene su SI jedinice. Ako nije drugačije naznačeno, dati podaci vrijede pri standardnim uslovima.
Vazopresin
Identifikatori
AliasiAVP
Vanjski ID-jeviOMIM: 192340 MGI: 88121 HomoloGene: 417 GeneCards: AVP
Lokacija gena (čovjek)
Hromosom 20 (čovjek)
Hrom.Hromosom 20 (čovjek)[1]
Hromosom 20 (čovjek)
Genomska lokacija za Vazopresin
Genomska lokacija za Vazopresin
Bend20p13Početak3,082,556 bp[1]
Kraj3,084,724 bp[1]
Lokacija gena (miš)
Hromosom 2 (miš)
Hrom.Hromosom 2 (miš)[2]
Hromosom 2 (miš)
Genomska lokacija za Vazopresin
Genomska lokacija za Vazopresin
Bend2 F1|2 63.24 cMPočetak130,422,540 bp[2]
Kraj130,424,474 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija• protein kinase activity
• hormone activity
• cysteine-type endopeptidase inhibitor activity involved in apoptotic process
• neurohypophyseal hormone activity
• signaling receptor binding
• V1A vasopressin receptor binding
• V1B vasopressin receptor binding
• neuropeptide hormone activity
Ćelijska komponenta• extracellular region
• citosol
• clathrin-coated vesicle membrane
• Vanćelijsko
• secretory granule
• dendrit
Biološki proces• negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
• Vazokonstrikcija
• negative regulation of release of cytochrome c from mitochondria
• ERK1 and ERK2 cascade
• water transport
• cell-cell signaling
• negative regulation of apoptotic process
• protein kinase C signaling
• generation of precursor metabolites and energy
• positive regulation of peptidyl-serine phosphorylation
• GO:1901313 positive regulation of gene expression
• renal water homeostasis
• GO:0072468 Transdukcija signala
• GO:0097285 apoptoza
• membrane organization
• regulation of signaling receptor activity
• G protein-coupled receptor signaling pathway
• maternal aggressive behavior
• positive regulation of systemic arterial blood pressure
• positive regulation of cytosolic calcium ion concentration
• negative regulation of female receptivity
• grooming behavior
• locomotory behavior
• positive regulation of cell population proliferation
• positive regulation of glutamate secretion
• GO:1904578 response to organic cyclic compound
• positive regulation of cell growth
• positive regulation of prostaglandin biosynthetic process
• positive regulation of cellular pH reduction
• response to testosterone
• response to nicotine
• socijalno ponašanje
• regulation of renal sodium excretion
• hyperosmotic salinity response
• maternal behavior
• Erekcija
• response to ethanol
• positive regulation of vasoconstriction
• multicellular organismal water homeostasis
• negative regulation of transmission of nerve impulse
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl