RAD51B

RAD51B
Identifiers
Aliases	RAD51B, R51H2, RAD51L1, REC2, RAD51 paralog B
External IDs	OMIM: 602948; MGI: 1099436; GeneCards: RAD51B
Gene location (Human) Chr. Chromosome 14 (human) Band 14q24.1 Start 67,819,779 bp End 68,730,218 bp
Gene location (Mouse) Chr. Chromosome 12 (mouse) Band 12|12 C3 Start 79,297,282 bp End 79,814,690 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve buccal mucosa cell testicle secondary oocyte body of uterus ventricular zone Achilles tendon gallbladder corpus callosum epithelium of colon Top expressed in blastocyst zygote spermatid embryo morula cumulus cell embryo ventricular zone tail of embryo uterus More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding nucleotide binding ATP-dependent activity, acting on DNA DNA strand exchange activity single-stranded DNA binding protein binding four-way junction DNA binding double-stranded DNA binding endodeoxyribonuclease activity ATP binding Cellular component replication fork nucleoplasm Rad51B-Rad51C-Rad51D-XRCC2 complex nucleus Biological process strand invasion response to ionizing radiation reciprocal meiotic recombination DNA recombination blood coagulation cellular response to DNA damage stimulus positive regulation of G2/M transition of mitotic cell cycle mitotic recombination DNA repair meiotic DNA recombinase assembly double-strand break repair via homologous recombination Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 5890 19363 Ensembl ENSG00000182185 ENSMUSG00000059060 UniProt O15315 O35719 RefSeq (mRNA) NM_002877 NM_133509 NM_133510 NM_001321809 NM_001321810 NM_001321812 NM_001321814 NM_001321815 NM_001321817 NM_001321818 NM_001321819 NM_001321821 NM_001252562 NM_009014 RefSeq (protein) NP_001308738 NP_001308739 NP_001308741 NP_001308743 NP_001308744 NP_001308746 NP_001308747 NP_001308748 NP_001308750 NP_002868 NP_598193 NP_598194 NP_001239491 NP_033040 Location (UCSC) Chr 14: 67.82 – 68.73 Mb Chr 12: 79.3 – 79.81 Mb PubMed search
Wikidata
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DNA repair protein RAD51 homolog 2 is a protein that in humans is encoded by the RAD51B gene (previously RAD51L1).